Green Coffee Bean Extract

$29.95

NPN: 80055920

Herbal Magic's Green coffee bean extract (GCBE) has shown to help increase weight loss by maintaining glucose homeostasis and playing a role in fat metabolism. Clinical trials demonstrate that GCBE significantly reduces body weight and BMI, while decreasing postload glycemia and increasing lean to fat mass ratio.

• Complements your Herbal Magic weight management program which includes a calorie reduced diet and regular activity.
• Helps support heart health.
• Helps maintain healthy blood pressure levels.
• Provides antioxidants.

• Core program product for clients aged 19+ in the Transformation stage of their weight loss programs.
• This product can be used as substitute for Green Tea Extract in the Motivation and Determination stages if XanthaLean cannot be taken.
• Optional product for those struggling to meet their weight loss goals or looking to boost their weight loss results.

Product Monograph for Herbal Magic

Green Coffee Bean Extract NPN 80055920

GENERAL INFORMATION

Herbal Magic’s Green Coffee Bean Extract acts as a complement to a healthy lifestyle that incorporates a calorie-reduced diet and regular physical activity for individuals involved in the Herbal Magic weight management program.

Green coffee bean extract (GCBE) has shown to help increase weight loss by maintaining glucose homeostasis and playing a role in fat metabolism. Clinical trials demonstrate that GCBE significantly reduces body weight and BMI, while decreasing post-load glycemia and increasing lean to fat mass ratio.

RECOMMENDED USES

  • Primary Use: Complements your Herbal Magic weight management program which includes a calorie reduced diet and regular activity.
  • Secondary Uses: Helps support heart health; Helps maintain healthy blood pressure levels; Provides antioxidants.

 

MECHANISM OF ACTION

Research Suggests

 

Green coffee bean extract (Coffea canephora)

GCBE contains a mixture of chlorogenic acid, polyphenols and 5-caffeylquinic acid. Green coffee beans are coffee beans in their raw, unroasted state which is not achieved in traditionally brewed coffee. Roasting of coffee beans removes a significant portion of the active ingredient chlorogenic acid.[i] Hence, Green coffee beans are one of the best natural sources for chlorogenic acid.[ii]

Herbal Magic’s Green Coffee Bean Extract (GCBE)is a  jitter free formula that contains less caffeine than a quarter cup of coffee daily (less than 2% caffeine/less than 20 mg daily), and is suitable for those with caffeine sensitivities.

GCBE is a 100% all-natural plant concentrate, with standardized bioactives providing 45% chlorogenic acids. Chlorogenic acids have been clinically proven to help induce weight loss.1

The beneficial health effects of chlorogenic acids are well known and have been documented. Various studies have suggested that chlorogenic acids from green coffee beans have been shown to influence postprandial blood sugar concentration, glucose tolerance, serum lipid concentration, and glucose absorption from the intestine. Chlorgenic acid inhibits glucose absorption in the small intestine via inhibition of the activity of glucose-6-phosphatase, limiting the release of glucose into circulation.[iii],[iv],[v],[vi]

When Green Coffee Bean Extract was studied,  the post prandial blood glucose levels of the participants taking GCBE were lower in comparison to control,  133 mg/dL vs. 148 mg/dL respectively (P<0.05).[vii] In another study comparing GCBE to instant coffee and decaffeinated coffee, results also indicated lower plasma glucose levels with GCBE. consumption. 1 hour post GCBE intake, the mean plasma glucose concentration was 6.23 mmol/l, versus 7.30 mmol/l with decaffeinated coffee intake and 8.25 mmol/l with instant coffee intake. It is thought that Chlorogenic acid might act by inhibiting glucose absorption in the small intestine. Due to the reduced availability of glucose as an energy source, the fat reserves are used for energy instead.[i] Therefore, chlorogenic acid can affect adipose metabolism.

Research further shows that GCBE has an effect on glucose and fat metabolism. The clinical benefits of this have been demonstrated in studies: participants lose weight and decrease their fat mass. In a 2012 study, lean mass to fat mass ratio was found to increase in the GCBE group compared to the placebo group: +4.1 +/- 0.7% vs. +1.6 +/- 0.6 respectively (<0.01).[ii]

Moreover, clinical trials have revealed a significant difference in body weight in groups taking GCBE when compared with placebo. In a clinical trial, participants consuming GCBE saw a reduction in body weight of up to 11 pounds compared to 5 pounds among people consuming the placebo, over a two month period.1

Research has been shown that GCBE can help support heart health and reduce blood pressure.[iii] When orally administered, chlorogenic acid is metabolized to ferulic acid in the liver and/or kidneys.[iv] Ferulic acid, which is a metabolite of GCBE containing chlorogenic acid, decreases blood pressure and improves vasoreactivity.[v],[vi] Blood pressure benefits have resulted from amounts as little as 140 mg of chlorogenic acids per day.[vii]

A multicenter, randomized, double-blind, placebo-controlled, parallel group study demonstrated that GCBE can reduce blood pressure in a dose-related manner. After 28 days, 93 mg, and 185 mg of supplementation: 1) significantly reduced systolic blood pressure (SBP) by -4.7±4.5 mmHg, and -5.6±4.2 mmHg respectively, and 2) significantly decreased diastolic blood pressure (DBP) by -3.2±3.2 mmHg, and -3.9±2.8 mmHg respectively, from the baseline, compared to placebo group.[viii]

These effects were further demonstrated when healthy men and women consumed 400 mg of Green Coffee Bean Extract (equivalent to 2 cups of coffee) in a randomized, double-blind, placebo-controlled, crossover trial. Relative to control, the mean post-treatment systolic blood pressure and diastolic blood pressure were significantly lower with chlorogenic acid. These findings further confirm that chlorogenic acid can help lower blood pressure acutely, an effect that, if sustained, would benefit cardiovascular health.[ix]

Moreover, GCBE has antioxidant effects. Fat cells store toxins which are released throughout the body during weight loss, [x],[xi] resulting in increased circulating concentrations of toxic pollutants. [xii],[xiii],[xiv] Antioxidants are required to help quench these toxins and reduce damage to surrounding environments.[xv],[xvi] GCBE provides antioxidants that helps eliminate these toxins, and also help prevent various kinds of diseases associated with oxidative stress, such as cardiovascular disease and some forms of cancer.

RECOMMENDED DOSAGE

For Ages 18+: 1 cap 3x/day with meals.

CAUTIONS AND WARNINGS

If you are breastfeeding, consult a health care practitioner prior to use.

DISEASE/CONDITION INTERACTIONS

If you are pregnant, do not use this product.

DRUG INTERATIONS

No Statement.

FORMULATION

Medicinal Ingredients per capsule:

Green coffee bean extract (7:1) (Coffea canephora) ........ 333.33 mg (2333 mg crude)

Standardized to:

45% chlorogenic acids and 10% 5-caffeylquinic acid

*Providing less than 2% caffeine (less than 20 mg/day)

Non-medicinal Ingredients:

Hypromellose, magnesium stearate.

Features:

  • Non-GMO
  • Vegan friendly
  • Gluten free
  • Dye free

REFERENCES

[i] Flanagan, J., Bily, A., Rolland, Y. and Roller, M. (2014), Lipolytic Activity of Svetol®, a Decaffeinated Green Coffee Bean Extract. Phytother. Res., 28: 946–948.

[ii] Onakapoya I,  Terry R, et al. The use of Green Coffee Extract as a Weight Loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. Gastroenterology Res Pract. 2011. pii: 382852.

[iii] Nardon K., Lemaire B. Lafay S. Green coffee extract Svetol can manage weight: a review. AgroFood industry hi-tech. 2007; 18(5:37-39.

[iv] Blums J, Lemaire B., Lafay Sophie, Effect of a Green Decaffeinated coffee extract on Glycaemia A pilot Prospective Clinical Study. Nutrafoods. 2007; 6(3) 13-17.

[v] E Thom., The effect of cholorgenic Acid Enriched Coffee on Glucose Absoption in Healthy Volunteers and Its Effect on Body Mass when used Long-term in Overweight and Obese People. The Journal of International Medical Research. 2007;35:900-908.

[vi] Henry-Vitrac CIbarra ARoller MMérillon JMVitrac X. Contribution of chlorogenic acids to the inhibition of human hepatic glucose-6-phosphatase activity in vitro by Svetol, a standardized decaffeinated green coffee extract. J Agric Food Chem. 2010 Apr 14;58(7):4141-4.

[vii] Blum J, Lemaire B, Lafay S. Effect of a green decaffeinated coffee extract on glycaemia. NutraFoods Res. 2007;6:13–7.

[8] Thom, E. (2007). The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people. Journal of International Medical Research, 35(6), 900-908.

[9] Dellalibera O, Lemaire B, Lafay S. Svetol® , green coffee extract, induces weight loss and increases the lean to fat mass ratio in volunteers with overweight problem. http://www.realdose.com/wp-content/uploads/2012/01/ Effect_of_Svetol_on_weight_loss_on_humans.pdf. Accessed MAy 21, 2015.

[10] Saito I, Tsuchida T, Watanabe T, et al: Effect of coffee bean extract in essential hypertension. Jpn J Med Pharm Sci 2002; 47: 67−74 (in Japanese).

[11] Olthof MR, Hollman PC, Michel N, et al: Chlorogenic acid, quercetin-3-rutinoside and black tea phenols are extensively metabolized in humans. J Nutr 2003; 133: 1806−1814.

[12] Suzuki A, Kagawa D, Ochiai R, Tokimitsu I, Saito I: Green coffee bean extract and its metabolites have a hypotensive effect in spontaneously hypertensive rats. Hypertens Res 2002; 25: 99−107.

[13] Ochiai R, Jokura H, Suzuki A, et al: Green coffee bean extract improves human vasoreactivity. Hypertens Res 2004; 27: 731−737.

[14] Watanabe, T., Arai, Y., Mitsui, Y., Kusaura, T., Okawa, W., Kajihara, Y., & Saito, I. (2006). The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension. Clinical and experimental hypertension, 28(5), 439-449.

[15] Kozuma, K., Tsuchiya, S., Kohori, J., Hase, T., & Tokimitsu, I. (2005). Antihypertensive effect of green coffee bean extract on mildly hypertensive subjects. Hypertension research, 28(9), 711-718.

[16] Mubarak, A., Bondonno, C. P., Liu, A. H., Considine, M. J., Rich, L., Mas, E., ... & Hodgson, J. M. (2012). Acute effects of chlorogenic acid on nitric oxide status, endothelial function, and blood pressure in healthy volunteers: a randomized trial. Journal of agricultural and food chemistry, 60(36), 9130-9136.

[17] Health Canada. Natural Health Products Directorate. Product Monographs. Green Coffee Bean 2014.  Available at: www.hc-sc.gc.ca Accessed May 21, 2015.

[18] Elobeid MA, Padilla MA, Brock DW, Ruden DM, Allison DB. Endocrine disruptors and obesity: an examination of selected persistent organic pollutants in the NHANES 1999-2002 data. Int J Environ Res Public Health. 2010 July 7(7):2988-3005. 

[19] Hue O, Marcotte J, Berrigan F, Simoneau M, Doré J, Marceau P, Marceau S, Tremblay A, Teasdale N. Increased plasma levels of toxic pollutants accompanying weight loss induced by hypocaloric diet or by bariatric surgery. Obes Surg.  2006 September 16(9):1145-54.

[20] Charlier C, Desaive C, Plomteux G. Human exposure to endocrine disrupters: consequences of gastroplasty on plasma concentration of toxic pollutants. nt J Obes Relat Metab Disord.  2002 November ;26(11):1465-8.
Clinical Toxicology Laboratory, University Hospital, Liege, Belgium.

[21] Lim JSSon HKPark SKJacobs DR JrLee DH. Int J Obes (Lond). Inverse associations between long-term weight change and serum concentrations of persistent organic pollutants.2011;35(5):744-7.

[22] Fang YZYang SWu G. Free radicals, antioxidants, and nutrition. Nutrition. 2002 Oct;18(10):872-9.

[23] Uttara B, Singh AV, Zamboni P, Mahajan R. Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options. Current Neuropharmacology. 2009;7(1):65-74.

 

RECOMMENDED DOSAGE

For Ages 18+: 1 cap 3x/day with meals.

CAUTIONS AND WARNINGS

If you are breastfeeding, consult a health care practitioner prior to use.

DISEASE/CONDITION INTERACTIONS

If you are pregnant, do not use this product

DRUG INTERATIONS

No Statement.

FORMULATION

Medicinal Ingredients per capsule:

Green coffee bean extract (7:1) (Coffea canephora) ........ 333.33 mg (2333 mg crude)

Standardized to:

45% chlorogenic acids and 10% 5-caffeylquinic acid

*Providing less than 2% caffeine (less than 20 mg/day)

Non-medicinal Ingredients:

Hypromellose, magnesium stearate.

Features:

  • Non-GMO
  • Vegan friendly
  • Gluten free
  • Dye free